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The Rouen metropolis is a land of industries. It is first that of textiles that develops, from the late nineteenth century, carried by cotton mills and port activities. Then the automobile, steel, chemical and refinery activities rise in power. Today, the territory is home to national and international industry flagships in the automotive (Renault, NextMove competitiveness cluster), aeronautics (Thales), pharmaceutical (Aspen, Sanofi), food (Ferrero, Nutriset, Touflet, Cargill), chemical (Laguerre Chimie) sectors… and is developing research clusters for an ecological and responsible industry.